PRESENT ONGOING DHEA RESEARCH UPDATE

As of August 4th, 2010 we have 160 pregnancies confirmed on DHEA supplemantation.  82 patients (51.3%) have delivered, 28 patients are ongoing (17.5%) and early pregnancy loss rate of 25.2%, low for an average age of all 160 patients of 37.5 years.  From an analysis of the total number of pregnant patients, 34 got pregnant on DHEA alone, 26 on oral fertility tables (aromatase inhibitors) 45 on COH with IUI and 55 with IVF/ICSI. Male to female baby ratio is 53% males to 47% females. This is in keeping with our previously published findings of an increased ratio of boys to girls in these conceptions using DHEA. We only had a 1% major congenital abnormality event (not life compatible). 

This very low congenital abnormality rate is likely accounted for by a dramatic reduction in aneuploidy rates in DHEA assisted embryo's, suggested  by first polar body analysis done at the Center for Human Reproduction in New York (personal communication to me from Dr. Norbert Gleicher, with whom we have co-published some articles in the Reproductive Scientific Literature, American and Canadian Fertility meetings in San Francisco and Montreal and in the Journal of Reproductive Biology and Endocrinology Oct. 2009).

Future Research Plans

We are presently doing studies on CoEnzime Q10 in  ladies (35 years to 46 years age), and in men with abnormal sperm parameters.  To date this aspect of our clinical research is showing great promise.  We will keep you informed.